Dichloromethane → methyl 3-[4-oxo-1'-(3-phenylpropyl)spiro[3H-chromene-2,4'-piperidine]-6-yl]prop-2-enoate

HRID 209531Notes

Reaction equation

HRID 209531 reaction equation
[Br:1][CH2:2][CH2:3][CH2:4][c:5]1[cH:6][cH:7][cH:8][cH:9][cH:10]1.[CH3:11][O:12][C:13]([CH:14]=[CH:15][c:16]1[cH:17][c:18]2[c:23]([cH:24][cH:25]1)[O:22][C:21]1([CH2:20][C:19]2=[O:38])[CH2:26][CH2:27][N:28]([C:31]([O:32][C:33]([CH3:34])([CH3:35])[CH3:36])=[O:37])[CH2:29][CH2:30]1)=[O:39].[Cl:40][CH2:41][Cl:42]>>[CH2:3]([CH2:4][c:5]1[cH:6][cH:7][cH:8][cH:9][cH:10]1)[CH2:31][N:28]1[CH2:27][CH2:26][C:21]2([CH2:20][C:19](=[O:38])[c:18]3[cH:17][c:16]([CH:15]=[CH:14][C:13]([O:12][CH3:11])=[O:39])[cH:25][cH:24][c:23]3[O:22]2)[CH2:30][CH2:29]1

Participants

4

Reactant 3

HCID 6344DichloromethaneHCID 12503(3-Bromopropyl)benzeneHCID 66932397tert-butyl 6-(3-methoxy-3-oxoprop-1-enyl)-4-oxospiro[3H-chromene-2,4'-piperidine]-1'-carboxylate

Product 1

HCID 66932375methyl 3-[4-oxo-1'-(3-phenylpropyl)spiro[3H-chromene-2,4'-piperidine]-6-yl]prop-2-enoate

Sources & evidence

ORD record
ord-dce550474c8547fc864f9a85c75f26f6
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (6/10)

Reaction notes

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