HuagongsheHuagongshe Chemistry Print Report · For research reference only
methyl 4-amino-2,2-dimethylbutanoate hydrochloride → HCID 67074248, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | methyl 4-amino-2,2-dimethylbutanoate hydrochloride | HCID 86628421 | — |
| Reactant | (S)-2-[Benzyloxycarbonyl-(2-oxo-ethyl)-amino]-propionic acid methyl ester | HCID 86638111 | — |
| Product | HCID 67074248 | HCID 67074248 | 90% |
Reaction Steps
In analogy to the procedure described in Example 12D, (S)-2-[benzyloxycarbonyl-(2-oxo-ethyl)-amino]-propionic acid methyl ester (intermediate 12C) and 4-amino-2,2-dimethyl-butyric acid methyl ester, hydrochloride (intermediate 27) gave the titled compound in 90% yield as light yellow oil. MS: 377.21 (MH+).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08445674B2 |
| Source dataset | uspto-grants-2013_05 |
| ORD ID | ord-f072e83e5ce44a33a887312c067050d8 |
| Source note | uspto-grants-2013_05 |