1,4-Dioxane → Tert-butyl 2-(2-cyano-6-(trifluoromethyl)quinolin-4-ylamino)acetate
Reaction equation
[NH2:18][CH2:19][C:20](=[O:21])[O:22][C:23]([CH3:24])([CH3:25])[CH3:26].[O:27]1[CH2:28][CH2:29][O:30][CH2:31][CH2:32]1.[OH:1][c:2]1[cH:3][c:4]([C:16]#[N:17])[n:5][c:6]2[cH:7][cH:8][c:9]([C:12]([F:13])([F:14])[F:15])[cH:10][c:11]12>>[c:2]1([NH:18][CH2:19][C:20](=[O:21])[O:22][C:23]([CH3:24])([CH3:25])[CH3:26])[cH:3][c:4]([C:16]#[N:17])[n:5][c:6]2[cH:7][cH:8][c:9]([C:12]([F:13])([F:14])[F:15])[cH:10][c:11]12Participants
4
Sources & evidence
- ORD record
- ord-0842d829953f4e558cbb9e5c350d8e55
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (6/10)
Reaction notes
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