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HRID2095557

反应详情

EQUATION

反应方程式

HRID 2095557 的结构方程式

REACTANTS

反应物

2
结构：O=C=Nc1cccc(Cl)c1
HCID17968

m-Chlorophenyl isocyanate

C7H4ClNO

结构：C[C@@H]1NCCN(CCCC(=O)N2CCC3(CC3)[C@H](O)C2)C1=O
HCID67074162

未命名化合物

2 次

PRODUCTS

生成物

1
结构：C[C@H]1C(=O)N(CCCC(=O)N2CCC3(CC3)[C@H](O)C2)CCN1C(=O)Nc1cccc(Cl)c1
HCID67074305

未命名化合物

收率 17%

PROCEDURE

实验过程

In analogy to the procedure described in Example 25, (S)-1-[4-((S)-4-hydroxy-6-aza-spiro[2.5]oct-6-yl)-4-oxo-butyl]-3-methyl-piperazin-2-one (intermediate 13) and 3-chlorophenyl isocyanate gave the titled compound in 17% yield as white foam. MS: 463.2 (MH+, Cl).