HRID2095564

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID14368497

未命名化合物

2 次

结构：C[C@@H]1NCCN(CCCC(=O)N2CCC3(CC3)[C@H](O)C2)C1=O

HCID67074162

未命名化合物

2 次

PRODUCTS

生成物

结构：C[C@H]1C(=O)N(CCCC(=O)N2CCC3(CC3)[C@H](O)C2)CCN1C(=O)Nc1ccc(C(F)(F)F)c(Cl)c1

HCID67086910

未命名化合物

收率 83%

PROCEDURE

实验过程

In analogy to the procedure described in Example 30, (S)-1-[4-((S)-4-hydroxy-6-aza-spiro[2.5]oct-6-yl)-4-oxo-butyl]-3-methyl-piperazin-2-one (intermediate 13) and 2-chloro-4-isocyanato-1-trifluoromethyl-benzene (intermediate 16) gave the titled compound in 83% yield as white foam. MS: 531.20 (MH+, 1Cl).