HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 15765405, compound → HCID 58232187, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 15765405 | HCID 15765405 | — |
| Reactant | HCID 67074162 | HCID 67074162 | — |
| Product | HCID 58232187 | HCID 58232187 | 68% |
Reaction Steps
In analogy to the procedure described in Example 30, (S)-1-[4-((S)-4-hydroxy-6-aza-spiro[2.5]oct-6-yl)-4-oxo-butyl]-3-methyl-piperazin-2-one (intermediate 13) and 2-chloro-4-isocyanato-1-trifluoromethoxy-benzene (intermediate 17) gave the titled compound in 68% yield as light brown foam. MS: 547.19 (MH+, 1Cl).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08445674B2 |
| Source dataset | uspto-grants-2013_05 |
| ORD ID | ord-b40d2603f6464262b0603feefe36e893 |
| Source note | uspto-grants-2013_05 |