HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methyl bromoacetate → 3-[(3-Chloro-4-trifluoromethyl-phenyl)-methoxycarbonylmethyl-amino]-propionic acid tert-butyl ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methyl bromoacetate | HCID 60984 | — |
| Reactant | 3-(3-Chloro-4-trifluoromethyl-phenylamino)-propionic acid tert-butyl ester | HCID 67074412 | — |
| Product | 3-[(3-Chloro-4-trifluoromethyl-phenyl)-methoxycarbonylmethyl-amino]-propionic acid tert-butyl ester | HCID 67074349 | 34% |
Reaction Steps
In analogy to the procedure described for intermediate 40B, 3-(3-chloro-4-trifluoromethyl-phenylamino)-propionic acid tert-butyl ester and methyl bromoacetate gave the title compound in 34% yield as yellow oil. MS: 396.12 (MH+, Cl).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08445674B2 |
| Source dataset | uspto-grants-2013_05 |
| ORD ID | ord-a1f7ea7645dd45419e6ac886b8b5b3bc |
| Source note | uspto-grants-2013_05 |