Methyl triflate → HCID 58158460, compound

Participants

Reaction Conditions

Reaction Steps

A mixture of ethyl 2-(4-fluorophenyl)-3-oxo-2,3-dihydro-1H-pyrazole-4-carboxylate (2.2 g, 8.9 mmol) and methyl trifluoromethanesulfonate (3 mL) was stirred at 80° C. for 40 min. The mixture was purified by silica gel column chromatography (NH silica gel, ethyl acetate/hexane=70/30→100/0) to give the title compound (1.6 g, 67%) as a pale-yellow solid.

Provenance & Evidence