HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methyl triflate → ethyl 1-methyl-2-(2-methylphenyl)-3-oxo-2,3-dihydro-1H-pyrazole-4-carboxylate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methyl triflate | HCID 9526 | — |
| Reactant | ethyl 5-hydroxy-1-(2-methylphenyl)-1H-pyrazole-4-carboxylate | HCID 10037547 | — |
| Product | ethyl 1-methyl-2-(2-methylphenyl)-3-oxo-2,3-dihydro-1H-pyrazole-4-carboxylate | HCID 58158463 | 66% |
Reaction Steps
In the same manner as in Reference Example 64 and using ethyl 2-(2-methylphenyl)-3-oxo-2,3-dihydro-1H-pyrazole-4-carboxylate (3.1 g, 12 mmol) and methyl trifluoromethanesulfonate (2.5 mL) as starting materials, the title compound (2.1 g, 66%) was obtained as a pale-yellow solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08445509B2 |
| Source dataset | uspto-grants-2013_05 |
| ORD ID | ord-5c1b46f53d9c458b8fd82763cd23c5df |
| Source note | uspto-grants-2013_05 |