Methyl triflate → HCID 58158541, compound

HRID 2095814Notes

Reaction equation

HRID 2095814 reaction equation
[Cl:1][C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][C:3]=1[N:8]1[C:12](=[O:13])[C:11]([C:14]([O:16][CH2:17][CH3:18])=[O:15])=[CH:10][NH:9]1.F[C:20](F)(F)S(OC)(=O)=O>>[Cl:1][C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][C:3]=1[N:8]1[C:12](=[O:13])[C:11]([C:14]([O:16][CH2:17][CH3:18])=[O:15])=[CH:10][N:9]1[CH3:20]

Participants

3

Reactant 2

HCID 9526Methyl triflateHCID 58158628HCID 58158628, compound

Product 1

HCID 58158541HCID 58158541, compoundYield 81%

Procedure

In the same manner as in Reference Example 64 and using ethyl 2-(2-chlorophenyl)-3-oxo-2,3-dihydro-1H-pyrazole-4-carboxylate (3.4 g, 12 mmol) and methyl trifluoromethanesulfonate (3 mL) as starting materials, the title compound (2.8 g, 81%) was obtained as a white solid.

Sources & evidence

ORD record
ord-03c3ec02c2dd494c85eefae905d75007
Source dataset
uspto-grants-2013_05
Patent number
US08445509B2

Reaction notes

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