m-Chloroperbenzoic acid → HCID 66968986, compound

Participants

Reaction Conditions

Reaction Steps

To a solution (100 mL) of 2-(3-fluorophenyl)-3-methylpyridine (4.83 g, 25.8 mmol) in ethyl acetate was added 3-chloroperbenzoic acid (7.1 g, 28.4 mmol), and the mixture was stirred at 50° C. for 5 hr. The disappearance of 3-chloroperbenzoic acid was confirmed using potassium iodide starch paper (manufactured by ADVANTEC MFS, INC), and the solvent was evaporated under reduced pressure. The residue was purified by silica gel column chromatography to give the title compound (4.26 g, 81%).

Provenance & Evidence