Pyridine → HCID 59769522, compound

Participants

Reaction Steps

To a mixture of tert-butyl 4-hydroxybutylcarbamate (3.83 g) obtained in Reference Synthetic Example 35 and ethyl acetate (20 mL) were added pyridine (1.80 mL) and acetic anhydride (2.27 g), and stirred at room temperature for 19 hrs. To the reaction solution was added ethyl acetate (100 mL), and washed with water (50 mL), aqueous solution of copper sulfate (30 mL), water (30 mL) and saturated brine (30 mL), followed by drying over anhydrous magnesium sulfate. The solution was concentrated under reduced pressure to give title compound as colorless oil (4.55 g).

Provenance & Evidence