1,4-Dioxaspiro[4.5]decan-8-one → HCID 59361631, compound

HRID 2096157Notes

Reaction equation

HRID 2096157 reaction equation
Br[C:2]1[CH:3]=[CH:4][C:5]([CH3:8])=[N:6][CH:7]=1.[O:9]1[C:13]2([CH2:18][CH2:17][C:16](=[O:19])[CH2:15][CH2:14]2)[O:12][CH2:11][CH2:10]1>CCOCC>[CH3:8][C:5]1[N:6]=[CH:7][C:2]([C:16]2([OH:19])[CH2:17][CH2:18][C:13]3([O:12][CH2:11][CH2:10][O:9]3)[CH2:14][CH2:15]2)=[CH:3][CH:4]=1

Participants

4

Reactant 2

HCID 5674151,4-Dioxaspiro[4.5]decan-8-oneHCID 12010205-Bromo-2-methylpyridine

Product 1

HCID 59361631HCID 59361631, compound

Reagents, catalysts & solvents 1

HCID 3283Diethyl EtherSolvent

Procedure

The title compound was prepared as a white solid from 5-bromo-2-methyl-pyridine (Acros Organics) and 1,4-dioxa-spiro[4.5]decan-8-one in ether using the procedure described in Step A of Example 1.

Sources & evidence

ORD record
ord-0be202f4775748e1b4f200675b0ab34b
Source dataset
uspto-grants-2013_05
Patent number
US08450304B2

Reaction notes

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