HuagongsheHuagongshe Chemistry Print Report · For research reference only
N-(azetidin-3-ylcarbamoylmethyl)-3-trifluoromethyl-benzamide → N-{[1-(4-Hydroxy-4-pyridin-3-yl-cyclohexyl)-azetidin-3-ylcarbamoyl]-methyl}-3-trifluoromethyl-benzamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | N-(azetidin-3-ylcarbamoylmethyl)-3-trifluoromethyl-benzamide | HCID 59361594 | — |
| Reactant | 4-Hydroxy-4-pyridin-3-yl-cyclohexanone | HCID 59361641 | — |
| Product | N-{[1-(4-Hydroxy-4-pyridin-3-yl-cyclohexyl)-azetidin-3-ylcarbamoyl]-methyl}-3-trifluoromethyl-benzamide | HCID 46241829 | — |
Reaction Steps
The title compound was prepared as yellow solid using the procedure described in Step E of Example 1 from reductive amination of 4-Hydroxy-4-pyridin-3-yl-cyclohexanone, as prepared in the previous step, and N-(azetidin-3-ylcarbamoylmethyl)-3-trifluoromethyl-benzamide.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08450304B2 |
| Source dataset | uspto-grants-2013_05 |
| ORD ID | ord-f13390adbf0541e9844981055cb2d3f2 |
| Source note | uspto-grants-2013_05 |