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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2096171Generated: November 3, 2026

2,5-Dibromopyridine → 8-(5-Bromopyridin-2-yl)-1,4-dioxaspiro[4.5]decan-8-ol

https://huagongshe.com/reaction/2096171

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2,5-DibromopyridineHCID 69353—
Reactant1,4-Dioxaspiro[4.5]decan-8-oneHCID 567415—
SolventDiethyl EtherHCID 3283—
Product8-(5-Bromopyridin-2-yl)-1,4-dioxaspiro[4.5]decan-8-olHCID 57803252—

Reaction Steps

The title compound was prepared as a white solid from 2,5-dibromo-pyridine (Aldrich) and 1,4-dioxa-spiro[4.5]decan-8-one in ether using the procedure described in Step A of Example 1.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08450304B2
Source datasetuspto-grants-2013_05
ORD IDord-f52150db8f96452792f2056dfba465e7
Source noteuspto-grants-2013_05