1,4-Dioxaspiro[4.5]decan-8-one → HCID 59361633, compound

HRID 2096173Notes

Reaction equation

HRID 2096173 reaction equation
Br[C:2]1[CH:3]=[CH:4][C:5]([N:8]([CH3:10])[CH3:9])=[N:6][CH:7]=1.[O:11]1[C:15]2([CH2:20][CH2:19][C:18](=[O:21])[CH2:17][CH2:16]2)[O:14][CH2:13][CH2:12]1>CCOCC>[CH3:9][N:8]([CH3:10])[C:5]1[N:6]=[CH:7][C:2]([C:18]2([OH:21])[CH2:19][CH2:20][C:15]3([O:14][CH2:13][CH2:12][O:11]3)[CH2:16][CH2:17]2)=[CH:3][CH:4]=1

Participants

4

Reactant 2

HCID 5674151,4-Dioxaspiro[4.5]decan-8-oneHCID 38030415-bromo-N,N-dimethylpyridin-2-amine

Product 1

HCID 59361633HCID 59361633, compound

Reagents, catalysts & solvents 1

HCID 3283Diethyl EtherSolvent

Procedure

The title compound was prepared as a white solid from 5-bromo-2-dimethylamino-pyridine (Indofine) and 1,4-dioxa-spiro[4.5]decan-8-one in ether using the procedure described in Step A of Example 1.

Sources & evidence

ORD record
ord-82883e15e4ef41e49d625027d3a8c170
Source dataset
uspto-grants-2013_05
Patent number
US08450304B2

Reaction notes

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