Pyrimidine, 5-bromo-2-methoxy- → HCID 59361570, compound

HRID 2096176Notes

Reaction equation

HRID 2096176 reaction equation
Br[C:2]1[CH:3]=[N:4][C:5]([O:8][CH3:9])=[N:6][CH:7]=1.[O:10]1[C:14]2([CH2:19][CH2:18][C:17](=[O:20])[CH2:16][CH2:15]2)[O:13][CH2:12][CH2:11]1>CCOCC>[CH3:9][O:8][C:5]1[N:4]=[CH:3][C:2]([C:17]2([OH:20])[CH2:18][CH2:19][C:14]3([O:13][CH2:12][CH2:11][O:10]3)[CH2:15][CH2:16]2)=[CH:7][N:6]=1

Participants

4

Reactant 2

HCID 139657Pyrimidine, 5-bromo-2-methoxy-HCID 5674151,4-Dioxaspiro[4.5]decan-8-one

Product 1

HCID 59361570HCID 59361570, compound

Reagents, catalysts & solvents 1

HCID 3283Diethyl EtherSolvent

Procedure

The title compound was prepared as a white solid from 5-bromo-2-methoxy-pyrimidine (Aldrich) and 1,4-dioxa-spiro[4.5]decan-8-one in ether using the procedure described in Step A of Example 1.

Sources & evidence

ORD record
ord-e75ab5ff42be4e958403744462af31e8
Source dataset
uspto-grants-2013_05
Patent number
US08450304B2

Reaction notes

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