5-Bromo-2,4-dimethoxypyrimidine → HCID 59361611, compound

HRID 2096178Notes

Reaction equation

HRID 2096178 reaction equation
Br[C:2]1[C:3]([O:10][CH3:11])=[N:4][C:5]([O:8][CH3:9])=[N:6][CH:7]=1.[O:12]1[C:16]2([CH2:21][CH2:20][C:19](=[O:22])[CH2:18][CH2:17]2)[O:15][CH2:14][CH2:13]1>CCOCC>[CH3:9][O:8][C:5]1[N:4]=[C:3]([O:10][CH3:11])[C:2]([C:19]2([OH:22])[CH2:20][CH2:21][C:16]3([O:15][CH2:14][CH2:13][O:12]3)[CH2:17][CH2:18]2)=[CH:7][N:6]=1

Participants

4

Reactant 2

HCID 2557195-Bromo-2,4-dimethoxypyrimidineHCID 5674151,4-Dioxaspiro[4.5]decan-8-one

Product 1

HCID 59361611HCID 59361611, compound

Reagents, catalysts & solvents 1

HCID 3283Diethyl EtherSolvent

Procedure

The title compound was prepared as a white solid from 5-bromo-2,4-dimethoxy-pyrimidine (Aldrich) and 1,4-dioxa-spiro[4.5]decan-8-one in ether using the procedure described in Step A of Example 1.

Sources & evidence

ORD record
ord-13ce3ae2e1954e96a0c2ef544e06aa39
Source dataset
uspto-grants-2013_05
Patent number
US08450304B2

Reaction notes

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