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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2096186Generated: November 1, 2026

4-Hydroxy-4-thiazol-2-yl-cyclohexanone → HCID 46240482, compound

https://huagongshe.com/reaction/2096186

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-Hydroxy-4-thiazol-2-yl-cyclohexanoneHCID 59017437—
ReactantN-(azetidin-3-ylcarbamoylmethyl)-3-trifluoromethyl-benzamideHCID 59361594—
ProductHCID 46240482HCID 46240482—

Reaction Steps

The title compounds were prepared as white solids from reductive amination of 4-hydroxy-4-thiazol-2-yl-cyclohexanone, as prepared in the previous step, and N-(azetidin-3-ylcarbamoylmethyl)-3-trifluoromethyl-benzamide using the procedure described in Step E of Example 1.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08450304B2
Source datasetuspto-grants-2013_05
ORD IDord-2ed19edeee1e44e39843fdf03981f281
Source noteuspto-grants-2013_05