2-Methylthiazole → HCID 58463977, compound
Reaction equation
[CH3:1][C:2]1[S:3][CH:4]=[CH:5][N:6]=1.[O:7]1[C:11]2([CH2:16][CH2:15][C:14](=[O:17])[CH2:13][CH2:12]2)[O:10][CH2:9][CH2:8]1>>[CH3:1][C:2]1[S:3][C:4]([C:14]2([OH:17])[CH2:15][CH2:16][C:11]3([O:10][CH2:9][CH2:8][O:7]3)[CH2:12][CH2:13]2)=[CH:5][N:6]=1Participants
3
Procedure
The title compound was prepared as a white solid from 2-methyl-thiazole (Aldrich) and 1,4-dioxa-spiro[4.5]decan-8-one using the procedure described in Step A of Example 33.
Sources & evidence
- ORD record
- ord-0f51e9f5fdeb437091392e0070bc2aa1
- Source dataset
- uspto-grants-2013_05
- Patent number
- US08450304B2
Reaction notes
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