HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 59017431, compound → N-({1-[4-Hydroxy-4-(2-methyl-thiazol-5-yl)-cyclohexyl]-azetidin-3-ylcarbamoyl}-methyl)-3-trifluoromethyl-benzamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 59017431 | HCID 59017431 | — |
| Reactant | N-(azetidin-3-ylcarbamoylmethyl)-3-trifluoromethyl-benzamide | HCID 59361594 | — |
| Product | N-({1-[4-Hydroxy-4-(2-methyl-thiazol-5-yl)-cyclohexyl]-azetidin-3-ylcarbamoyl}-methyl)-3-trifluoromethyl-benzamide | HCID 46240783 | — |
Reaction Steps
The title compounds were prepared as white solids from reductive amination of 4-hydroxy-4(-methyl-thiazol-5-yl)-cyclohexanone, as prepared in the previous step, and N-(azetidin-3-ylcarbamoylmethyl)-3-trifluoromethyl-benzamide using the procedure described in Step E of Example 1.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08450304B2 |
| Source dataset | uspto-grants-2013_05 |
| ORD ID | ord-fe4565a6909d446ca73f06cfd075c402 |
| Source note | uspto-grants-2013_05 |