2-Isopropylthiazole → 8-(2-Isopropyl-1,3-thiazol-5-yl)-1,4-dioxaspiro[4.5]decan-8-ol

HRID 2096199Notes

Reaction equation

HRID 2096199 reaction equation
[CH:1]([C:4]1[S:5][CH:6]=[CH:7][N:8]=1)([CH3:3])[CH3:2].[O:9]1[C:13]2([CH2:18][CH2:17][C:16](=[O:19])[CH2:15][CH2:14]2)[O:12][CH2:11][CH2:10]1>>[CH:1]([C:4]1[S:5][C:6]([C:16]2([OH:19])[CH2:17][CH2:18][C:13]3([O:12][CH2:11][CH2:10][O:9]3)[CH2:14][CH2:15]2)=[CH:7][N:8]=1)([CH3:3])[CH3:2]

Participants

3

Reactant 2

HCID 850542-IsopropylthiazoleHCID 5674151,4-Dioxaspiro[4.5]decan-8-one

Product 1

HCID 595561458-(2-Isopropyl-1,3-thiazol-5-yl)-1,4-dioxaspiro[4.5]decan-8-ol

Procedure

The title compound was prepared as a white solid from 2-iso-propyl-thiazole and 1,4-dioxa-spiro[4.5]decan-8-one using the procedure described in Step A of Example 33.

Sources & evidence

ORD record
ord-d9c8072f92ac49019b51dcdc3ea0a08c
Source dataset
uspto-grants-2013_05
Patent number
US08450304B2

Reaction notes

Loading…