1,4-Dioxaspiro[4.5]decan-8-one → HCID 59361596, compound

HRID 2096202Notes

Reaction equation

HRID 2096202 reaction equation
[CH3:1][Si:2]([CH3:11])([CH3:10])[C:3]#[C:4][C:5]1[S:6][CH:7]=[CH:8][N:9]=1.[O:12]1[C:16]2([CH2:21][CH2:20][C:19](=[O:22])[CH2:18][CH2:17]2)[O:15][CH2:14][CH2:13]1>>[CH3:11][Si:2]([CH3:10])([CH3:1])[C:3]#[C:4][C:5]1[S:6][C:7]([C:19]2([OH:22])[CH2:20][CH2:21][C:16]3([O:15][CH2:14][CH2:13][O:12]3)[CH2:17][CH2:18]2)=[CH:8][N:9]=1

Participants

3

Reactant 2

HCID 5674151,4-Dioxaspiro[4.5]decan-8-oneHCID 11622446Thiazole, 2-[(trimethylsilyl)ethynyl]-

Product 1

HCID 59361596HCID 59361596, compound

Procedure

The title compound was prepared as a white solid from 2-trimethylsilanylethynyl-thiazole, as prepared in the previous step, and 1,4-dioxa-spiro[4.5]decan-8-one using the procedure described in Step A of Example 33.

Sources & evidence

ORD record
ord-4b5c0ca1ea9a438a8400b260b2664dbf
Source dataset
uspto-grants-2013_05
Patent number
US08450304B2

Reaction notes

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