HuagongsheHuagongshe Chemistry Print Report · For research reference only
Tetrabutylammonium Fluoride → HCID 46240685, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Tetrabutylammonium Fluoride | HCID 2724141 | — |
| Reactant | N-(azetidin-3-ylcarbamoylmethyl)-3-trifluoromethyl-benzamide | HCID 59361594 | — |
| Reactant | HCID 59361602 | HCID 59361602 | — |
| Product | HCID 46240685 | HCID 46240685 | — |
Reaction Steps
The title compounds were prepared as white solids from reductive amination of 4-hydroxy-4-(2-trimethylsilanylethynyl-thiazol-5-yl)-cyclohexanone, as prepared in the previous step, and N-(azetidin-3-ylcarbamoylmethyl)-3-trifluoromethyl-benzamide using the procedure described in Step E of Example 1 followed by TBAF work-up.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08450304B2 |
| Source dataset | uspto-grants-2013_05 |
| ORD ID | ord-3cf12b228f9648b79c3dd1b1644a5cfb |
| Source note | uspto-grants-2013_05 |