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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2096204Generated: October 26, 2026

1,4-Dioxaspiro[4.5]decan-8-one → 8-(2-Methylsulfanyl-thiazol-5-yl)-1,4-dioxa-spiro[4.5]decan-8-ol

https://huagongshe.com/reaction/2096204

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1,4-Dioxaspiro[4.5]decan-8-oneHCID 567415—
Reactant2-(Methylthio)thiazoleHCID 2760100—
Product8-(2-Methylsulfanyl-thiazol-5-yl)-1,4-dioxa-spiro[4.5]decan-8-olHCID 59361637—

Reaction Steps

The title compound was prepared as a white solid from 2-methylsulfanyl-thiazole (Aldrich) and 1,4-dioxa-spiro[4.5]decan-8-one using the procedure described in Step A of Example 33.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08450304B2
Source datasetuspto-grants-2013_05
ORD IDord-70fe0edc3b9b401da51b6ed8df12de19
Source noteuspto-grants-2013_05