反应详情

The title compounds were prepared as white solids from reductive amination of 8-(2-methylsulfanyl-thiazol-5-yl)-1,4-dioxa-spiro[4.5]decan-8-ol, as prepared in the previous step, and N-(azetidin-3-ylcarbamoylmethyl)-3-trifluoromethyl-benzamide using the procedure described in Step E of Example 1.