1,4-Dioxaspiro[4.5]decan-8-one → HCID 59361634, compound

HRID 2096218Notes

Reaction equation

HRID 2096218 reaction equation
[CH3:1][N:2]([CH3:9])[CH2:3][C:4]1[S:5][CH:6]=[CH:7][N:8]=1.[O:10]1[C:14]2([CH2:19][CH2:18][C:17](=[O:20])[CH2:16][CH2:15]2)[O:13][CH2:12][CH2:11]1>CCOCC>[CH3:1][N:2]([CH2:3][C:4]1[S:5][C:6]([C:17]2([OH:20])[CH2:18][CH2:19][C:14]3([O:13][CH2:12][CH2:11][O:10]3)[CH2:15][CH2:16]2)=[CH:7][N:8]=1)[CH3:9]

Participants

4

Reactant 2

HCID 5674151,4-Dioxaspiro[4.5]decan-8-oneHCID 17842470HCID 17842470, compound

Product 1

HCID 59361634HCID 59361634, compound

Reagents, catalysts & solvents 1

HCID 3283Diethyl EtherSolvent

Procedure

The title compound was prepared as a white solid from dimethyl-thiazol-2-ylmethyl-amine, as prepared in the previous step, and 1,4-dioxa-spiro[4.5]decan-8-one in ether using the procedure described in Step A of Example 33.

Sources & evidence

ORD record
ord-bace432af1ad4e57bd57d5efb96c5b2e
Source dataset
uspto-grants-2013_05
Patent number
US08450304B2

Reaction notes

Loading…