HuagongsheHuagongshe Chemistry Print Report · For research reference only
Trifluoroacetic acid → N-(Azetidin-3-ylcarbamoylmethyl)-3-trifluoromethyl-5-fluoro-benzamide TFA salt
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Trifluoroacetic acid | HCID 6422 | — |
| Reactant | 3-[2-(3-Trifluoromethyl-5-fluoro-benzoylamino)-acetylamino]-azetidine-1-carboxylic acid tert-butyl ester | HCID 59361584 | — |
| Product | N-(Azetidin-3-ylcarbamoylmethyl)-3-trifluoromethyl-5-fluoro-benzamide TFA salt | HCID 86642253 | — |
Reaction Steps
The title compound was prepared as colorless oil from TFA de-protection of 3-[2-(5-fluoro-3-trifluoromethyl-benzoylamino)-acetylamino]-azetidine-1-carboxylic acid tert-butylester, as prepared in the previous step, using the procedure described in Step D of Example 1.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08450304B2 |
| Source dataset | uspto-grants-2013_05 |
| ORD ID | ord-48e0a58c55b64fbda5555c52dbac55a8 |
| Source note | uspto-grants-2013_05 |