HuagongsheHuagongshe Chemistry Print Report · For research reference only
Trifluoroacetic acid → N-(Azetidin-3-ylcarbamoylmethyl)-2,5-bis-trifluoromethyl-benzamide TFA salt
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Trifluoroacetic acid | HCID 6422 | — |
| Reactant | 3-[2-(2,5-Bis-trifluoromethyl-benzoylamino)-acetylamino]-azetidine-1-carboxylic acid tert-butylester | HCID 59361607 | — |
| Product | N-(Azetidin-3-ylcarbamoylmethyl)-2,5-bis-trifluoromethyl-benzamide TFA salt | HCID 86642256 | — |
Reaction Steps
The title compound was prepared as colorless oil from TFA de-protection of 3-[2-(2,5-bis-trifluoromethyl-benzoylamino)-acetylamino]-azetidine-1-carboxylic acid tert-butylester using the procedure described in Step D of Example 1.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08450304B2 |
| Source dataset | uspto-grants-2013_05 |
| ORD ID | ord-624d23afc55f4136b4ac18ebcd6586f4 |
| Source note | uspto-grants-2013_05 |