Diisopropylethylamine → HCID 58346320, compound

Participants

Reaction Steps

70 mg (0.28 mmol) 5-amino-1,3-dihydrospiro[inden-2,3′-pyrrolo[2,3-b]pyridin]-2′(1′H)-one, 80 mg (0.28 mmol) (6-chloro-pyrimidin-4-yl)-(2.3-difluoro-phenyl)-methanone and 60 μL DIPEA in 600 μL dimethylsulphoxide were stirred for 1 h at 80° C. After cooling the reaction mixture was combined with approx. 10 mL ice water. The liquid was decanted off and the residue was dissolved in DCM and MeOH. After drying with sodium sulphate the mixture was filtered and the solvent was evaporated down. The residue was triturated with ether, suction filtered and dried.

Provenance & Evidence