4-Methylthiazole → HCID 44552755, compound
Reaction equation
Cl[C:2]1[C:3]2[N:11]=[N:10][N:9]([CH2:12][C:13]3[CH:18]=[CH:17][CH:16]=[C:15]([C:19]([OH:22])([CH3:21])[CH3:20])[N:14]=3)[C:4]=2[N:5]=[C:6]([NH2:8])[N:7]=1.[CH3:23][C:24]1[N:25]=[CH:26][S:27][CH:28]=1>>[CH3:23][C:24]1[N:25]=[C:26]([C:2]2[C:3]3[N:11]=[N:10][N:9]([CH2:12][C:13]4[CH:18]=[CH:17][CH:16]=[C:15]([C:19]([OH:22])([CH3:21])[CH3:20])[N:14]=4)[C:4]=3[N:5]=[C:6]([NH2:8])[N:7]=2)[S:27][CH:28]=1Participants
3
Procedure
This is prepared from 7-chloro-3-(6-[1-hydroxy-1-methylethyl]pyrid-2-ylmethyl)-3H-[1,2,3]triazolo[4,5-d]pyrimidin-5-amine and 4-methylthiazole by the method of Example 38.
Sources & evidence
- ORD record
- ord-1940a188bbbd4f66857d8dced2badcc5
- Source dataset
- uspto-grants-2013_05
- Patent number
- US08450328B2
Reaction notes
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