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HRID2096827

反应详情

EQUATION

反应方程式

HRID 2096827 的结构方程式

REACTANTS

反应物

2
结构：COC(=O)c1ccc(B(O)O)c(F)c1
HCID24824345

[2-Fluoro-4-(methoxycarbonyl)phenyl]boronic acid

C8H8BFO4

结构：CC(c1ccc(Br)cc1Cl)C(O)(c1ccc2oc(=O)n(C)c2c1)C(F)(F)F
HCID66696981

未命名化合物

PRODUCTS

生成物

1
结构：COC(=O)c1ccc(-c2ccc(C(C)C(O)(c3ccc4oc(=O)n(C)c4c3)C(F)(F)F)c(Cl)c2)c(F)c1
HCID66696990

未命名化合物

PROCEDURE

实验过程

The title compound was prepared in analogy to Example 117 from 5-[2-(4-bromo-2-chloro-phenyl)-1-hydroxy-1-trifluoromethyl-propyl]-3-methyl-3H-benzooxazol-2-one (obtained in Example 116, step 8) by Suzuki coupling with 2-fluoro-4-methoxycarbonylphenylboronic acid [CAS Reg. No. 603122-84-5]. MS (m/e)=538.3 [M+H+].