3-Ethoxy-4-(pyridin-4-ylamino)cyclobut-3-ene-1,2-dione → 3-(Pyridin-4-ylamino)-4-[6-(pyridin-3-yloxy)-hexylamino]-cyclobut-3-ene-1,2-dione

HRID 2097323Notes

Reaction equation

HRID 2097323 reaction equation
C(O[C:4]1[C:5](=[O:16])[C:6](=[O:15])[C:7]=1[NH:8][C:9]1[CH:14]=[CH:13][N:12]=[CH:11][CH:10]=1)C.[N:17]1[CH:22]=[CH:21][CH:20]=[C:19]([O:23][CH2:24][CH2:25][CH2:26][CH2:27][CH2:28][CH2:29][NH2:30])[CH:18]=1>>[N:12]1[CH:11]=[CH:10][C:9]([NH:8][C:7]2[C:6](=[O:15])[C:5](=[O:16])[C:4]=2[NH:30][CH2:29][CH2:28][CH2:27][CH2:26][CH2:25][CH2:24][O:23][C:19]2[CH:18]=[N:17][CH:22]=[CH:21][CH:20]=2)=[CH:14][CH:13]=1

Participants

3

Reactant 2

HCID 106803193-Ethoxy-4-(pyridin-4-ylamino)cyclobut-3-ene-1,2-dioneHCID 231324436-(Pyridin-3-yloxy)-hexylamine

Product 1

HCID 231324233-(Pyridin-4-ylamino)-4-[6-(pyridin-3-yloxy)-hexylamino]-cyclobut-3-ene-1,2-dione

Procedure

The title compound was prepared according to the procedure described in example 1B starting from 3-ethoxy-4-(pyridin-4-yl-amino)-3-cyclobutene-1,2-dione prepared according to example 7A and 6-(pyridin-3-yloxy)-hexylamine.

Workup

  1. customprepared

Sources & evidence

ORD record
ord-77adf805a32e4f27b686ef8e0e8d392e
Source dataset
uspto-grants-2013_05
Patent number
US08450348B2

Reaction notes

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