4-Phenoxyphenethylamine → HCID 11646704, compound

HRID 2097324Notes

Reaction equation

HRID 2097324 reaction equation
C(O[C:4]1[C:5](=[O:16])[C:6](=[O:15])[C:7]=1[NH:8][C:9]1[CH:14]=[CH:13][N:12]=[CH:11][CH:10]=1)C.[O:17]([C:24]1[CH:29]=[CH:28][C:27]([CH2:30][CH2:31][NH2:32])=[CH:26][CH:25]=1)[C:18]1[CH:23]=[CH:22][CH:21]=[CH:20][CH:19]=1>>[O:17]([C:24]1[CH:25]=[CH:26][C:27]([CH2:30][CH2:31][NH:32][C:4]2[C:5](=[O:16])[C:6](=[O:15])[C:7]=2[NH:8][C:9]2[CH:10]=[CH:11][N:12]=[CH:13][CH:14]=2)=[CH:28][CH:29]=1)[C:18]1[CH:23]=[CH:22][CH:21]=[CH:20][CH:19]=1

Participants

3

Reactant 2

HCID 1455354-PhenoxyphenethylamineHCID 106803193-Ethoxy-4-(pyridin-4-ylamino)cyclobut-3-ene-1,2-dione

Product 1

HCID 11646704HCID 11646704, compound

Procedure

The title compound was prepared according to the procedure described in example 1B starting from 3-ethoxy-4-(pyridin-4-yl-amino)-3-cyclobutene-1,2-dione prepared according to example 7A and 2-(4-phenoxyphenyl)-ethylamine. The reaction mixture was heated to reflux for 2 hours instead of stirring 18 h at r.t.

Workup

  1. customprepared
  2. temperatureThe reaction mixture was heated
  3. temperatureto reflux for 2 hours instead

Sources & evidence

ORD record
ord-f1c051d7f93a4db7890584a932be41f7
Source dataset
uspto-grants-2013_05
Patent number
US08450348B2

Reaction notes

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