4-(4-chlorophenoxy)benzylamine → HCID 11611151, compound

HRID 2097337Notes

Reaction equation

HRID 2097337 reaction equation
C(O[C:4]1[C:5](=[O:16])[C:6](=[O:15])[C:7]=1[NH:8][C:9]1[CH:10]=[N:11][CH:12]=[CH:13][CH:14]=1)C.[Cl:17][C:18]1[CH:32]=[CH:31][C:21]([O:22][C:23]2[CH:30]=[CH:29][C:26]([CH2:27][NH2:28])=[CH:25][CH:24]=2)=[CH:20][CH:19]=1>>[Cl:17][C:18]1[CH:32]=[CH:31][C:21]([O:22][C:23]2[CH:30]=[CH:29][C:26]([CH2:27][NH:28][C:4]3[C:5](=[O:16])[C:6](=[O:15])[C:7]=3[NH:8][C:9]3[CH:10]=[N:11][CH:12]=[CH:13][CH:14]=3)=[CH:25][CH:24]=2)=[CH:20][CH:19]=1

Participants

3

Reactant 2

HCID 45826784-(4-chlorophenoxy)benzylamineHCID 105129913-(Pyridin-3-ylamino)-4-ethoxy-cyclobut-3-ene-1,2-dione

Product 1

HCID 11611151HCID 11611151, compoundYield 68%

Procedure

The title compound was prepared according to the procedure described in example 1B starting from 3-ethoxy-4-(pyridin-3-yl-amino)-3-cyclobutene-1,2-dione prepared according to example 1A and 4-(4-chlorophenoxy)-benzylamine.

Workup

  1. customprepared

Sources & evidence

ORD record
ord-6405864a1737446ea96c3fd0e5390a4f
Source dataset
uspto-grants-2013_05
Patent number
US08450348B2

Reaction notes

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