(4-Phenoxyphenyl)methanamine → 3-[4-Phenoxybenzylamino]-4-(pyridin-4-yl-amino)-cyclobut-3-ene-1,2-dione

HRID 2097341Notes

Reaction equation

HRID 2097341 reaction equation
C(O[C:4]1[C:5](=[O:16])[C:6](=[O:15])[C:7]=1[NH:8][C:9]1[CH:14]=[CH:13][N:12]=[CH:11][CH:10]=1)C.[O:17]([C:24]1[CH:31]=[CH:30][C:27]([CH2:28][NH2:29])=[CH:26][CH:25]=1)[C:18]1[CH:23]=[CH:22][CH:21]=[CH:20][CH:19]=1>>[O:17]([C:24]1[CH:25]=[CH:26][C:27]([CH2:28][NH:29][C:4]2[C:5](=[O:16])[C:6](=[O:15])[C:7]=2[NH:8][C:9]2[CH:10]=[CH:11][N:12]=[CH:13][CH:14]=2)=[CH:30][CH:31]=1)[C:18]1[CH:19]=[CH:20][CH:21]=[CH:22][CH:23]=1

Participants

3

Reactant 2

HCID 2760343(4-Phenoxyphenyl)methanamineHCID 106803193-Ethoxy-4-(pyridin-4-ylamino)cyclobut-3-ene-1,2-dione

Product 1

HCID 231324253-[4-Phenoxybenzylamino]-4-(pyridin-4-yl-amino)-cyclobut-3-ene-1,2-dioneYield 55%

Procedure

The title compound was prepared according to the procedure described in example 1B starting from 3-ethoxy-4-(pyridin-4-yl-amino)-3-cyclobutene-1,2-dione prepared according to example 7A and 4-phenoxybenzylamine.

Workup

  1. customprepared

Sources & evidence

ORD record
ord-263ad167371a485e979e9bd55d14c751
Source dataset
uspto-grants-2013_05
Patent number
US08450348B2

Reaction notes

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