3-(Pyridin-3-ylamino)-4-ethoxy-cyclobut-3-ene-1,2-dione → HCID 23132445, compound

HRID 2097342Notes

Reaction equation

HRID 2097342 reaction equation
C(O[C:4]1[C:5](=[O:16])[C:6](=[O:15])[C:7]=1[NH:8][C:9]1[CH:10]=[N:11][CH:12]=[CH:13][CH:14]=1)C.[Cl:17][C:18]1[CH:33]=[CH:32][C:21]([O:22][CH2:23][C:24]2[CH:25]=[C:26]([CH:29]=[CH:30][CH:31]=2)[CH2:27][NH2:28])=[CH:20][CH:19]=1>>[Cl:17][C:18]1[CH:19]=[CH:20][C:21]([O:22][CH2:23][C:24]2[CH:25]=[C:26]([CH:29]=[CH:30][CH:31]=2)[CH2:27][NH:28][C:4]2[C:5](=[O:16])[C:6](=[O:15])[C:7]=2[NH:8][C:9]2[CH:10]=[N:11][CH:12]=[CH:13][CH:14]=2)=[CH:32][CH:33]=1

Participants

3

Reactant 2

HCID 105129913-(Pyridin-3-ylamino)-4-ethoxy-cyclobut-3-ene-1,2-dioneHCID 23132447HCID 23132447, compound

Product 1

HCID 23132445HCID 23132445, compoundYield 65%

Procedure

The title compound was prepared according to the procedure described in example 1B starting from 3-ethoxy-4-(pyridine-3-yl-amino)-3-cyclobutene-1,2-dione prepared according to example 1A and 3-(4-chlorophenoxy-methyl)-benzylamine.

Workup

  1. customprepared

Sources & evidence

ORD record
ord-71d0a6f854644e8e8d75c8c30efc0ed7
Source dataset
uspto-grants-2013_05
Patent number
US08450348B2

Reaction notes

Loading…