2-(1-Benzylpiperidin-4-yl)ethan-1-amine → HCID 11646798, compound

HRID 2097345Notes

Reaction equation

HRID 2097345 reaction equation
C(O[C:4]1[C:5](=[O:16])[C:6](=[O:15])[C:7]=1[NH:8][C:9]1[CH:14]=[CH:13][N:12]=[CH:11][CH:10]=1)C.[CH2:17]([N:24]1[CH2:29][CH2:28][CH:27]([CH2:30][CH2:31][NH2:32])[CH2:26][CH2:25]1)[C:18]1[CH:23]=[CH:22][CH:21]=[CH:20][CH:19]=1>>[CH2:17]([N:24]1[CH2:29][CH2:28][CH:27]([CH2:30][CH2:31][NH:32][C:4]2[C:5](=[O:16])[C:6](=[O:15])[C:7]=2[NH:8][C:9]2[CH:10]=[CH:11][N:12]=[CH:13][CH:14]=2)[CH2:26][CH2:25]1)[C:18]1[CH:23]=[CH:22][CH:21]=[CH:20][CH:19]=1

Participants

3

Reactant 2

HCID 18670022-(1-Benzylpiperidin-4-yl)ethan-1-amineHCID 106803193-Ethoxy-4-(pyridin-4-ylamino)cyclobut-3-ene-1,2-dione

Product 1

HCID 11646798HCID 11646798, compoundYield 71%

Procedure

The title compound was prepared according to the procedure described in example 37 starting from 3-ethoxy-4-(pyridine-4-yl-amino)-3-cyclobutene-1,2-dione prepared according to example 7A and 2-(1-benzylpiperidin-4-yl)-ethylamine.

Workup

  1. customprepared

Sources & evidence

ORD record
ord-618c404f21f24c2b8b247c762a3fe686
Source dataset
uspto-grants-2013_05
Patent number
US08450348B2

Reaction notes

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