反应详情

Reaction and post treatment were carried out in the same manner as in Example 4-(c) except for using 5.84 g (11.9 mmol) of 2-(3-cyclopropoxy-4-difluoromethoxyphenyl)-3-ethyl-5-(2-trimethylsilylethoxymethyl)-1,5-dihydropyrrolo[2,3-d]pyridazin-4-one obtained in Example 5-(b) in place of 2-(3-cyclopropoxy-4-difluoromethoxyphenyl)-3-methyl-5-(2-trimethylsilylethoxymethyl)-1,5-dihydropyrrolo-[2,3-d]pyridazin-4-one, whereby 4.41 g of the title compound was obtained as a white solid substantially quantitatively.

1. customReaction and post treatment