反应详情

Reaction and post treatment were carried out in the same manner as in Example 13-(c) except for using 1.22 g (2.28 mmol) of 2-(3-cyclopropoxy-4-difluoromethoxyphenyl)-3-isopropoxymethyl-5-(2-trimethylsilylethoxymethyl)-1,5-dihydropyrrolo[2,3-d]pyridazin-4-one obtained in the same manner as in Example 60-(b) in place of 3-cyclobutoxymethyl-2-(3-cyclopropoxy-4-difluoromethoxyphenyl)-5-(2-trimethylsilylethoxymethyl)-1,5-dihydropyrrolo[2,3-d]-pyridazin-4-one, whereby 619 mg of the title compound was obtained as a white solid. (Yield: 67%)

1. customReaction and post treatment