HuagongsheHuagongshe Chemistry Print Report · For research reference only
Aminopyrazine → HCID 66710701, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Aminopyrazine | HCID 78747 | — |
| Reactant | 3-(5-Bromo-pyridin-2-yloxy)-azetidine-1-carboxylic acid 4-nitro-phenyl ester | HCID 58073119 | — |
| Product | HCID 66710701 | HCID 66710701 | 56.4% |
Reaction Steps
This compound was prepared by the method outlined for example 5 step 4. Thus 3-(5-bromo-pyridin-2-yloxy)-azetidine-1-carboxylic acid 4-nitro-phenyl ester (905 mg, 2.30 mmol) was reacted with 2-aminopyrazine (243 mg, 2.53 mmol) to afford the title compound (454 mg, 56%) as off white solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08450346B2 |
| Source dataset | uspto-grants-2013_05 |
| ORD ID | ord-8df45810ef754918ae5c55b949d583b0 |
| Source note | uspto-grants-2013_05 |