HuagongsheHuagongshe Chemistry Print Report · For research reference only
Dichloromethane → HCID 58941813, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Dichloromethane | HCID 6344 | — |
| Reactant | Triacetoxyperiodinane | HCID 159087 | — |
| Reactant | N-(3-chloro-4-fluorophenyl)-4-(hydroxymethyl)-1,2,5-oxadiazole-3-carboxamide | HCID 58941855 | — |
| Solvent | Sodium Bicarbonate | HCID 516892 | — |
| Product | HCID 58941813 | HCID 58941813 | — |
Reaction Steps
A solution of N-(3-chloro-4-fluorophenyl)-4-(hydroxymethyl)-1,2,5-oxadiazole-3-carboxamide (8.50 g, 31.3 mmol), Dess-Martin periodinane (14.6 g, 34.4 mmol) and DCM (400 mL) was stirred at 25° C. for 3 h. The reaction was diluted with a saturated sodium bicarbonate solution and extracted with ethyl acetate three times, dried with sodium sulfate, filtered, and concentrated in vacuo.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08450351B2 |
| Source dataset | uspto-grants-2013_05 |
| ORD ID | ord-968e50d692504bf28cc95c45f216293d |
| Source note | uspto-grants-2013_05 |