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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2097773Generated: October 30, 2026

2-Amino-4-chlorobenzenethiol → N-{5-chloro-2-[(1H-imidazol-2-ylmethyl)thio]phenyl}-1-benzofuran-2-sulfonamide

https://huagongshe.com/reaction/2097773

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Amino-4-chlorobenzenethiolHCID 12000—
Reactant2-(chloromethyl)-1H-imidazoleHCID 425763—
Reactant1-Benzofuran-2-sulfonyl chlorideHCID 2795172—
ProductN-{5-chloro-2-[(1H-imidazol-2-ylmethyl)thio]phenyl}-1-benzofuran-2-sulfonamideHCID 57377452—

Reaction Steps

Following General Procedure A, B, the title compound was prepared from 2-Amino-4-chloro-benzenethiol, 2-chloromethyl-1H-imidazole and 1-benzofuran-2-sulfonyl chloride.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08450367B2
Source datasetuspto-grants-2013_05
ORD IDord-9ee4843e67564f6eb535abd254d12a11
Source noteuspto-grants-2013_05