HuagongsheHuagongshe Chemistry Print Report · For research reference only
Bromine → 6-Amino-7-bromobenzothiazole
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Bromine | HCID 24408 | — |
| Reactant | 6-Aminobenzothiazole | HCID 68288 | — |
| Solvent | Chloroform | HCID 6212 | — |
| Product | 6-Amino-7-bromobenzothiazole | HCID 4712620 | 129.3% |
Reaction Steps
To a solution of benzo[d]thiazol-6-amine (100 mg, 0.67 mmol) in 6 ml CHCl3 was added Br2 (42 mg, 0.27 mmol) in CHCl3 (10 ml) dropwise about 15 min. The mixture was concentrated under reduced pressure, and the residue was crystallized from DCM:MeOH (5:1) to give 7-bromobenzo[d]thiazol-6-amine (80 mg, 80%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08450363B2 |
| Source dataset | uspto-grants-2013_05 |
| ORD ID | ord-2fe915dc73fd49e0a31073ba3ac9bdf6 |
| Source note | uspto-grants-2013_05 |