HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-(Isoquinolin-5-YL)acetic acid → Methyl 4-bromo-2-(2-(isoquinolin-5-yl)acetamido)thiophene-3-carboxylate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-(Isoquinolin-5-YL)acetic acid | HCID 12018708 | — |
| Reactant | Methyl 2-amino-4-bromothiophene-3-carboxylate | HCID 68754257 | — |
| Product | Methyl 4-bromo-2-(2-(isoquinolin-5-yl)acetamido)thiophene-3-carboxylate | HCID 59636688 | — |
Reaction Steps
The title compound was prepared from 2-(isoquinolin-5-yl)acetic acid (427 mg, 2.18 mmol) and methyl 2-amino-4-bromothiophene-3-carboxylate (514 mg, 2.18 mmol) according to protocol A. Retention time (min)=1.634, method [1], MS (ESI) 405.0 (M+H).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08450363B2 |
| Source dataset | uspto-grants-2013_05 |
| ORD ID | ord-8fe3567463d046a6a0cb852113f5e714 |
| Source note | uspto-grants-2013_05 |