3-Aminothiophene-2-carboxamide → 3-(2-(Quinolin-5-yl)acetamido)thiophene-2-carboxamide

HRID 2097985Notes

Reaction equation

HRID 2097985 reaction equation
[N:1]1[C:10]2[C:5](=[C:6]([CH2:11][C:12]([OH:14])=O)[CH:7]=[CH:8][CH:9]=2)[CH:4]=[CH:3][CH:2]=1.[NH2:15][C:16]1[CH:20]=[CH:19][S:18][C:17]=1[C:21]([NH2:23])=[O:22]>>[N:1]1[C:10]2[C:5](=[C:6]([CH2:11][C:12]([NH:15][C:16]3[CH:20]=[CH:19][S:18][C:17]=3[C:21]([NH2:23])=[O:22])=[O:14])[CH:7]=[CH:8][CH:9]=2)[CH:4]=[CH:3][CH:2]=1

Participants

3

Reactant 2

HCID 5189933-Aminothiophene-2-carboxamideHCID 205339092-(Quinolin-5-yl)acetic acid

Product 1

HCID 687563723-(2-(Quinolin-5-yl)acetamido)thiophene-2-carboxamide

Procedure

The title compound was prepared from 2-(quinolin-5-yl)acetic acid and 3-aminothiophene-2-carboxamide using protocol B. Method[1], MS (ESI) 312.1 [M+H], Retention time=0.351 min.

Sources & evidence

ORD record
ord-9700e1d31bb2467c81f04835ed6e3752
Source dataset
uspto-grants-2013_05
Patent number
US08450363B2

Reaction notes

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