HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-(Quinolin-5-yl)acetic acid → Methyl 4-bromo-2-(2-(quinolin-5-yl)acetamido)thiophene-3-carboxylate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-(Quinolin-5-yl)acetic acid | HCID 20533909 | — |
| Reactant | Methyl 2-amino-4-bromothiophene-3-carboxylate | HCID 68754257 | — |
| Product | Methyl 4-bromo-2-(2-(quinolin-5-yl)acetamido)thiophene-3-carboxylate | HCID 68754644 | 49% |
Reaction Steps
The title compound was prepared from methyl 2-amino-4-bromothiophene-3-carboxylate (660 mg, 2.8 mmol) and 2-(quinolin-5-yl)acetic acid using protocol A. 560 mg (49% yield). Method [1]: rt=1.666 min; MH+ 405/407.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08450363B2 |
| Source dataset | uspto-grants-2013_05 |
| ORD ID | ord-1bfe9c4b0df343ebbf481479ec271179 |
| Source note | uspto-grants-2013_05 |