HCID 68782483, compound → HCID 178521252, compound

HRID 2098069Notes

Reaction equation

HRID 2098069 reaction equation
[Cl:1][C:2]1[C:3]([C:8]2[NH:12][CH:11]=[N:10][N:9]=2)=[C:4]([NH2:7])[S:5][CH:6]=1.[O:13]=[C:14]1[CH2:23][CH2:22][C:21]2[C:16](=[CH:17][CH:18]=[CH:19][N:20]=2)[N:15]1[CH2:24][C:25](O)=[O:26]>>[Cl:1][C:2]1[C:3]([C:8]2[N:12]=[CH:11][NH:10][N:9]=2)=[C:4]([NH:7][C:25](=[O:26])[CH2:24][N:15]2[C:16]3[C:21](=[N:20][CH:19]=[CH:18][CH:17]=3)[CH2:22][CH2:23][C:14]2=[O:13])[S:5][CH:6]=1

Participants

3

Reactant 2

HCID 68782483HCID 68782483, compoundHCID 178509327HCID 178509327, compound

Product 1

HCID 178521252HCID 178521252, compound

Procedure

The titled compound was synthesized from 4-chloro-3-(4H-1,2,4-triazol-3-yl)thiophen-2-amine and 2-(2-oxo-3,4-dihydro-1,5-naphthyridin-1(2H)-yl)acetic acid via protocol A. LCMS method [4], retention time=1.035; MS (ESI) 389.1 (MH+, 35Cl).

Sources & evidence

ORD record
ord-3742c3a1c5c14b3ab2427b9450917499
Source dataset
uspto-grants-2013_05
Patent number
US08450363B2

Reaction notes

Loading…