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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2098093Generated: October 30, 2026

4-bromo-3-(4H-1,2,4-triazol-3-yl)thiophen-2-amine → HCID 56665247, compound

https://huagongshe.com/reaction/2098093

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-bromo-3-(4H-1,2,4-triazol-3-yl)thiophen-2-amineHCID 59636686—
ReactantHCID 68785094HCID 68785094—
ProductHCID 56665247HCID 56665247—

Reaction Steps

The title compound was prepared from 2-(2-oxo-6-(trifluoromethoxy)quinolin-1(2H)-yl)acetic acid (40 mg, 0.14 mmol) and 4-bromo-3-(1H-1,2,4-triazol-5-yl)thiophen-2-amine (28 mg, 0.11 mmol) according to protocol A. Retention time (min)=6.06, method [7], MS (ESI) 514.0 (M+H); 1H NMR (300 MHz, CD3C1) δ 7.85 (d, J=9.35 Hz, 1H), 7.73 (s, 1H), 7.50 (s, 1H), 7.44-7.41 (m, 1H), 7.35-7.33 (m, 1H), 6.97 (d, J=9.9 Hz, 1H), 6.95 (s, 1H), 5.31 (s, 2H).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08450363B2
Source datasetuspto-grants-2013_05
ORD IDord-3a6daa7cc406453880230bb4077e1182
Source noteuspto-grants-2013_05