2-Chloro-3-nitrothiophene → HCID 68755304, compound

HRID 2098112Notes

Reaction equation

HRID 2098112 reaction equation
Cl[C:2]1[S:3][CH:4]=[CH:5][C:6]=1[N+:7]([O-:9])=[O:8].[CH3:10][C:11]1[N:12]=[C:13]([Sn](CCCC)(CCCC)CCCC)[S:14][CH:15]=1>>[CH3:10][C:11]1[N:12]=[C:13]([C:2]2[S:3][CH:4]=[CH:5][C:6]=2[N+:7]([O-:9])=[O:8])[S:14][CH:15]=1

Participants

3

Reactant 2

HCID 2201862-Chloro-3-nitrothiopheneHCID 164271304-Methyl-2-(tributylstannyl)-1,3-thiazole

Product 1

HCID 68755304HCID 68755304, compound

Procedure

4-Methyl-2-(3-nitrothiophen-2-yl)thiazole was prepared from 2-chloro-3-nitrothiophene (219 mg, 1.34 mmol) and 4-methyl-2-(tributylstannyl)thiazole (520 mg, 1.34 mmol) according to protocol E. Retention time (min)=2.462, method [1], MS (ESI) 227.0 (M+H).

Sources & evidence

ORD record
ord-bf60902e64b4408180b9d3ea48cf1395
Source dataset
uspto-grants-2013_05
Patent number
US08450363B2

Reaction notes

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